Three-dimensional biofabrication of an aragonite-enriched self-hardening bone graft substitute and assessment of its osteogenicity in vitro and in vivo

Yunsong Shi, Ruijun He, Xiangyu Deng, Zengwu Shao, Davide Deganello, Chunze Yan, Zhidao Xia

Table 2 Range analysis of compression strength and porosity of hydroxyapatite/aragonite

Factors Pressure (MPa) Printing speed (mm/s) Distance between strands (mm) Compression strength k1 2.01 1.55 1.54 k2 1.35 1.44 1.44 k3 0.78 1.15 1.16 R 1.23 0.4 0.38 Porosity k1 39.1 40.0 39.3 k2 27.3 36.0 38.0 k3 39.2 39.7 38.3 R 11.9 3.0 1.0