Hyaluronic acid-based hydrogels with tobacco mosaic virus containing cell adhesive peptide induce bone repair in normal and osteoporotic rats
Jishan Yuan1, Panita Maturavongsadit2,3, Zhihui Zhou1, Bin Lv1, Yuan Lin4, Jia Yang2, Jittima Amie Luckanagul5,6,*(
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Figure 1.. Schematic illustration of our study design. Methacrylated hyaluronic acid (MeHA) was synthesised and used with incorporated virus particles as a hydrogel structural platform to fill skull defects in osteoporotic and normal Sprague-Dawley rats. The RGD mutant TMV graphic was generated from PyMol with coordinates 2TMV from the Protein Data Bank (www.rcsb.org) and created with BioRender.com. OVX: ovariectomised; RGD: arginyl-glycyl-aspartic acid; TMV: tobacco mosaic virus.
