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Figure 2.. The SARS-CoV-2 spike protein bound to the ACE2 receptor. (A) The spike protein RBD (light blue, purple) is shown containing the receptor-binding motif (purple) while at the interface of the ACE2 receptor (tan). (B) Interface residues of the RBD (purple) are shown interacting with ACE2 residues in direct contact (red) or extended direct contact (blue) with the RBD. Figure reprinted from Lam et al.⁶ Licensed under CC BY 4.0. ACE2: angiotensin converting enzyme II; RBD: receptor-binding domain; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2.