Plant-produced recombinant SARS-CoV-2 receptor-binding domain; an economical, scalable biomaterial source for COVID-19 diagnosis
Kaewta Rattanapisit1, Gorawit Yusakul2, Balamurugan Shanmugaraj1, Kittinop Kittirotruji1, Phassorn Suwatsrisakul1, Eakachai Prompetchara3,4, Suthira Taychakhoonavud5,*(
), Waranyoo Phoolcharoen6,7,*()
), Waranyoo Phoolcharoen6,7,*()
.
Figure 5.. Representative test strips showing the results of serum samples collected from different patients in Thailand. The test sample is added to the sample well of the test cassette, where AuNP-RBD-IgY conjugates react with human anti-SARS-CoV-2 IgG and IgM in the sample. The sample then migrates through capillary action through the test and control lines. Sample #2 was found to be negative for both IgM and IgG, #86 was positive for IgM and IgG, while #32 was positive for IgM only. AuNPs: gold nanoparticles; C: control line; G: test line for human IgG; M: test line for human IgM; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2.
