Biofunctional magnesium coating of implant materials by physical vapour deposition
Qingchuan Wang, Weidan Wang, Yanfang Li, Weirong Li, Lili Tan, Ke Yang
Table 1 Summary of the biofunctions of magnesium (Mg) coating on different implant materials.
Substrate material Fabrication method Degradation behaviour Osteogenic property Angiogenic property Antimicrobial property References
AZ31 Vapour deposition Corrosion resistance improved 28
AZ31 Vapour deposition Comparable to the un-coated 6N-Mg 20
AZ31 Vapour deposition + hot press and HIP processes Corrosion resistance improved 29
Ti6Al4V Arc ion plating Continuous release with Mg degradation Enhanced new bone regenerating ability in vivo Accelerated blood vessel formation around the scaffold Strong killing effect of pure Mg film on Staphylococcus aureus 24, 26, 30, 31
Ti6Al4V Arc ion plating Sustained at least for 14 days Restrained peri-implant osteolysis Cu addition enhanced the antibacterial property of Mg coatings 27, 32
Cold-rolled steel plates Radio-frequency magnetron sputtering Corrosion rate greatly decreased 22
Oxidized Si wafer Physical vapor deposition Grains remain intact 48 hours after implantation Thinner fibrous capsule formed than titanium control samples 23
PEEK Vapour deposition Lower degradation rate without galvanic corrosion The antibacterial rate reached 99% when co-cultured for 12 hours 25