Preclinical evaluation of acute systemic toxicity of magnesium incorporated poly(lactic-co-glycolic acid) porous scaffolds by three-dimensional printing

Jing Long, Bin Teng, Wei Zhang, Long Li, Ming Zhang, Yingqi Chen, Zhenyu Yao, Xiangbo Meng, Xinluan Wang, Ling Qin, Yuxiao Lai

Additional Table 3 Effect of pH value on in vivo acute systemic toxicity.

Group Reagent Male mice (n) Female mice (n) Death rate (%) MEM (pH 7.0) MEM 5 5 0 MEM (pH 10.0) MEM 5 5 0 PT15M (pH 7.0) MEM 5 5 67 PT15M (pH 10.0) MEM 5 5 100