Jing Long 1, Bin Teng 2, Wei Zhang 1, Long Li 1,3, Ming Zhang 3, Yingqi Chen 3, Zhenyu Yao 1, Xiangbo Meng 1, Xinluan Wang 1, Ling Qin 1,4, Yuxiao Lai 1,2,5,*( )
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Figure 2.. In vitro immersion degradation behaviour of scaffolds. (A) Changes in the pH value of different solutions used to soak the PT15M scaffold at 37°C for 24, 48, and 72 hours. (B, C) The concentrations of Mg ions (B) and Ca ions (C) released into serum-free MEM after incubation with PT15M at 37°C for 24, 48, and 72 hours. In the test results, MEM has a higher baseline as it contains calcium chloride. (D) The pH value, Mg, and Ca ion concentrations of MEM incubated with PT, PT5M, PT10M, and PT15M scaffolds at 37°C for 72 hours. Data are expressed as the mean ± SD. (n = 3 and experiments were repeated by twice). Ca: calcium; MEM: serum-free minimum essential medium; Mg: magnesium; PT: poly(lactic-co-glycolic acid)/beta-tricalcium phosphate porous composite scaffolds; PT5M: poly(lactic-co-glycolic acid)/beta-tricalcium phosphate/5 wt% Mg porous composite scaffolds; PT10M: poly(lactic-co-glycolic acid)/beta-tricalcium phosphate/10 wt% Mg porous composite scaffolds; PT15M: poly(lactic-co-glycolic acid)/beta-tricalcium phosphate/15 wt% Mg porous composite scaffolds.
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