A brief history of the development of stromal stem cells (stem cells of the skeleton)

James T. Triffitt

Figure 1. (A) Culture flask of adherent rabbit bone marrow stromal fibroblasts growing as single colonies from single-cell suspensions of marrow stroma; these called colony forming units fibroblastic (CFU-F). (B) Alexander Friedenstein (1924–1998) in research discussions whilst visiting the MRC Bone Research Laboratory, Oxford, UK in the early 1980s.