Osteoarthritis animal models for biomaterial-assisted osteochondral regeneration

Yi Wang, Yangyang Chen, Yulong Wei

Figure 2. Safranin O and fast green staining of wild–type mouse knee joints at the medial site at 3 months post–sham (A) or post–DMM (B) surgery. DMM surgery was performed by transecting the medial meniscotibial ligament of the knee joint. Sham surgery serves as a control with the meniscotibial ligament intact. Scale bar: 200 μm. AC: articular cartilage; DMM: destabilisation of the medial meniscus; M: meniscus; S: synovium; SB: subchondral bone.