Figure 1. Illustrations of harvesting functional mesenchymal stem cells from osteo-organoids in vivo. The gelatin scaffolds loaded with rhBMP-2 are lyophilised and frozen for later use. In the experiment, the scaffolds were transplanted into the muscles of both hind limbs of mice. After 6 days, the osteo-organoids were removed in situ, followed by digestion with digestive enzyme mixture to obtain odMSCs. Created with Vectornator 5.4.0. MSCs: mesenchymal stem cells; odMSCs: osteo-organoid-derived MSCs; rhBMP-2: recombinant human bone morphogenetic protein-2.
Figure 1. Illustrations of harvesting functional mesenchymal stem cells from osteo-organoids in vivo. The gelatin scaffolds loaded with rhBMP-2 are lyophilised and frozen for later use. In the experiment, the scaffolds were transplanted into the muscles of both hind limbs of mice. After 6 days, the osteo-organoids were removed in situ, followed by digestion with digestive enzyme mixture to obtain odMSCs. Created with Vectornator 5.4.0. MSCs: mesenchymal stem cells; odMSCs: osteo-organoid-derived MSCs; rhBMP-2: recombinant human bone morphogenetic protein-2.
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