Special Issue

Special Issue: Covid-19: Challenges and Opportunities to Biomaterials Science and Translational Medicine

• EDITORIAL

  Using biomaterials research to address the challenges raised by the COVID-19 pandemic

  Qian Wang
  2021, 2(1):  1-2.  doi:10.3877/cma.j.issn.2096-112X.2021.01.001

  
  

  VIEWPOINT

  Development of personal protective equipment for the COVID-19 pandemic in Thailand and technical aspects of testing gown materials
  

  Visarut Buranasudja, Anongnat Somwangthanaroj, Suched Likitlersuang, Tirawat Boonyatee, Chartchalerm Isarankura-Na-Ayudhya, Jittima Amie Luckanagul

  2021, 2(1):  3-9.  doi:10.3877/cma.j.issn.2096-112X.2021.01.002
  

  
  

  REVIEW

  Physicochemical properties of respiratory droplets and their role in COVID-19 pandemics: a critical review
  

  Ting Ge, Shengfeng Cheng

  2021, 2(1):  10-18.  doi:10.3877/cma.j.issn.2096-112X.2021.01.003

  The coronavirus causing COVID-19 relies on respiratory droplets as the main carrier for its transmission. Understanding the physical characteristics of respiratory droplets and their fate after being released into air plays a crucial role in helping develop mitigating measures and policies to fight the ongoing pandemic that plagues the world.

  
  

  Recombinant adeno-associated virus-based gene therapy combined with tissue engineering for musculoskeletal regenerative medicine

  Yiqing Wang, Xiangyu Chu, Bing Wang

  2021, 2(1):  19-29.  doi:10.3877/cma.j.issn.2096-112X.2021.01.004
  

  A schematic diagram illustrating recombinant adeno-associated viral (rAAV)-based gene therapy combined with a tissue-engineered biomaterial scaffold. rAAV-modified stem cells and gene-activated biomaterials can be applied to bone, vertebral disc, cartilage or muscle to treat multiple musculoskeletal disorders.

  
  
  A biomaterials viewpoint for the 2020 SARS-CoV-2 vaccine development
  

  Isak Jatoi, Jingyu Fan

  2021, 2(1):  30-42.  doi:10.3877/cma.j.issn.2096-112X.2021.01.005
  

  Four vaccine types derived from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus are depicted, namely, DNA-based, viral vector, RNA-based, and protein subunit vaccines. Vaccine uptake, processing, and presentation by an antigen-presenting cell (APC) are also illustrated for these four vaccine mechanisms.

  
  

  
  

  RESEARCH ARTICLE

  Plant-produced recombinant SARS-CoV-2 receptor-binding domain; an economical, scalable biomaterial source for COVID-19 diagnosis
  

  Kaewta Rattanapisit, Gorawit Yusakul, Balamurugan Shanmugaraj, Kittinop Kittirotruji, Phassorn Suwatsrisakul, Eakachai Prompetchara, Suthira Taychakhoonavud, Waranyoo Phoolcharoen

  2021, 2(1):  43-49.  doi:10.3877/cma.j.issn.2096-112X.2021.01.006
  

  Plant-produced recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD) was used to develop a lateral flow immunoassay strip (LFIA) for detecting IgM/IgG antibodies.

  
  
  Fate and transport of enveloped viruses in indoor built spaces - through understanding vaccinia virus and surface interactions
  

  Dahae Seong, Monchupa Kingsak, Yuan Lin, Qian Wang, Shamia Hoque

  2021, 2(1):  50-59.  doi:10.3877/cma.j.issn.2096-112X.2021.01.007

  To limit transmission due to infectious droplets we must understand, “What factors control the transport, deposition, adhesion, and persistence of pathogens indoors?” The pandemic has reinforced the necessity of establishing baseline information on how viruses under indoor environmental conditions optimize survivability and transmission. Virus-surface interactions investigations using vaccinia virus sheds light on part of the picture.

Pubdate： 2021-03-28    Viewed： 460